Losartan Potassium: Management of hypertension and may have a role in patients who develop cough with angiotensin converting enzyme (ACE) inhibitors and to reduce the risk of stroke in patients with left ventricular hypertrophy and in the treatment of diabetic nephropathy.
Hydrochlorothiazide: Treatment of edema associated with heart failure and with renal hepatic disorders. It is also used in hypertension, either alone or together with other antihypertensives eg, ACE inhibitors and β-blockers. Treatment of edema accompanying syndrome, prevention of water retention associated with corticosteroids and estrogens, treatment of renal calculus formation in patients with hypercalciuria.